Telfin 1% Cream

✔️ Uses of Telfin 1% Cream

• Fungal skin Infections

✔️ How Telfin 1% Cream works?

Telfin 1% Cream is an antifungal medication that treats skin infections. It works by killing the fungi on the skin by destroying their cell membrane.

✔️ Side Effects of Telfin 1% Cream

• Application site reactions (burning, irritation, itching, and redness)
• Skin peeling
• Rash
• Indigestion
• Abnormal liver enzyme
• Itching
• Skin itching
• Discoloration of the skin
• Dry flaky skin

✔️ Quick Suggestions:

• Telfin 1% Cream helps treat skin infections caused by many different types of fungi.
• Finish the full course of treatment even if you feel better.
• It can take a few weeks for the infection to clear and a few months before the skin returns to its normal color.
• Apply an amount sufficient to cover the affected area and 1 inch of the immediate surrounding skin.
• It can make your skin more sensitive to the sun. Use broad-spectrum sunscreen and protective clothing when outdoors.
• Avoid getting in the eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.
• Inform your doctor if the infection has not cleared up after four weeks of treatment.

✔️ Indication of Telfin 1% Cream

Telfin 1% Cream (Terbinafine) is used to treat a wide range of fungal infections of the skin and nails, including ringworm. It works by killing the fungi that cause the infection.

✔️ Pharmacology

By blocking the enzyme squalene epoxidase, the allylamine antifungal terbinafine prevents the biosynthesis of ergosterol, a crucial part of fungal cell membranes. Fungal cells die as a result, but not because of a lack of ergosterol; rather, it happens as a result of increased membrane permeability caused by the buildup of high squalene concentrations. Terbinafine hydrochloride can kill the fungus, depending on the drug's concentration and the in vitro tested fungal species. The clinical relevance of the in vitro data is unknown, though. Both in vitro and in clinical infections, terbinafine has been demonstrated to be effective against the majority of strains of the following microorganisms: Trichophyton Mentagrophyte and Trichophyton rubrum.

✔️ Dosage & Administration of Telfin 1% Cream

Terbinafine Cream: 

• You can use terbinafine cream once or twice daily.
• Before applying the terbinafine cream, thoroughly clean and dry the affected areas.
• Apply a thin layer of the cream to the affected skin and the surrounding area, then gently rub it in.

The application may be covered with a gauze strip in the event of intertriginous infections (submammary, interdigital, intergluteal, or inguinal), especially at night. The following are the likely treatment durations:

• 1 to 2 weeks for tinea corporis and cruris.
• One week for tinnitus
• 2 weeks for cutaneous candidiasis
• 2 weeks for pityriasis Versicolor

Within a few days, the clinical symptoms are typically relieved. Recurrence is more likely with irregular use or early treatment termination. After two weeks, if there are still no signs of recovery, the diagnosis should be verified.

✔️ Interaction

Terbinafine is an inhibitor of the isoenzyme CYP450 2D6, according to in vivo studies. Tricyclic antidepressants, selective serotonin reuptake inhibitors, -receptor blockers, class 1C antiarrhythmic medications (like fluoro Carney and propafenone), and monoamine oxidase type inhibitors are among the classes of medications primarily metabolized by CYP450 2D6 isoenzymes. B. Terbinafine co-administration should be closely monitored, and the dose of the metabolite 2D6 may need to be decreased.

✔️ Contraindications

Terbinafine tablets and creams are contraindicated in people allergic to terbinafine.

✔️ Pregnancy & Lactation

Animal studies on fetal toxicity and fertility have not revealed any negative effects. Terbinafine should not be used in pregnant women because there is no clinical evidence that the potential benefits outweigh the potential risks. Because terbinafine is excreted in human milk, breastfeeding mothers shouldn't receive terbinafine treatment.

✔️ Precautions & Warnings

Terbinafine Cream is for external use only. Avoid contact with eyes.

Terbinafine is not recommended for use in children and adolescents (aged below 18 years).

✔️ Storage Conditions

Store in a cool and dry place, below 30°C, and protect from light.